Chemistry of Peptide-Oligonucleotide Conjugates: A Review

Chemistry of Peptide-Oligonucleotide Conjugates: A Review

Peptide-oligonucleotide conjugates (POCs) represent one of the increasingly successful albeit costly approaches to increasing the cellular uptake, tissue delivery, bioavailability, and, thus, overall efficiency of therapeutic nucleic acids, such as, antisense oligonucleotides and small interfering R...

Full description

Bibliographic Details
Main Authors: Kristina Klabenkova, Alesya Fokina, Dmitry Stetsenko
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Molecules
Subjects:
cell-penetrating peptide
nucleic acid therapeutic
antisense oligonucleotide
small interfering RNA (siRNA)
peptide nucleic acid (PNA)
locked nucleic acid (LNA)
Online Access:https://www.mdpi.com/1420-3049/26/17/5420

Internet

https://www.mdpi.com/1420-3049/26/17/5420

Similar Items