Preconditioning of murine mesenchymal stem cells synergistically enhanced immunomodulation and osteogenesis

Preconditioning of murine mesenchymal stem cells synergistically enhanced immunomodulation and osteogenesis

Abstract Background Mesenchymal stem cells (MSCs) are capable of immunomodulation and tissue regeneration, highlighting their potential translational application for treating inflammatory bone disorders. MSC-mediated immunomodulation is regulated by proinflammatory cytokines and pathogen-associated...

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Bibliographic Details
Main Authors: Tzuhua Lin, Jukka Pajarinen, Akira Nabeshima, Laura Lu, Karthik Nathan, Eemeli Jämsen, Zhenyu Yao, Stuart B. Goodman
Format: Article
Language:English
Published: BMC 2017-12-01
Series:Stem Cell Research & Therapy
Subjects:
Mesenchymal stem cells
Immunomodulation
Macrophage polarization
Osteogenesis
Prostaglandin E2
Online Access:http://link.springer.com/article/10.1186/s13287-017-0730-z

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http://link.springer.com/article/10.1186/s13287-017-0730-z

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