Mice fed a lipogenic methionine-choline-deficient diet develop hypermetabolism coincident with hepatic suppression of SCD-1 s⃞

Mice fed a lipogenic methionine-choline-deficient diet develop hypermetabolism coincident with hepatic suppression of SCD-1 s⃞

Lipogenic diets that are completely devoid of methionine and choline (MCD) induce hepatic steatosis. MCD feeding also provokes systemic weight loss, for unclear reasons. In this study, we found that MCD feeding causes profound hepatic suppression of the gene encoding stearoyl-coenzyme A desaturase-1...

Full description

Bibliographic Details
Main Authors: Gizem Rizki, Lorenzo Arnaboldi, Bianca Gabrielli, Jim Yan, Gene S. Lee, Ray K. Ng, Scott M. Turner, Thomas M. Badger, Robert E. Pitas, Jacquelyn J. Maher
Format: Article
Language:English
Published: Elsevier 2006-10-01
Series:Journal of Lipid Research
Subjects:
liver
fatty liver
steatosis
lipogenesis
fatty acid
oxidation
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520434157

Internet

http://www.sciencedirect.com/science/article/pii/S0022227520434157

Similar Items