Differential methylation at MHC in CD4+ T cells is associated with multiple sclerosis independently of HLA-DRB1
Abstract Background Although many genetic variants have been associated with multiple sclerosis (MS) risk, they do not explain all the disease risk and there remains uncertainty as to how these variants contribute to disease. DNA methylation is an epigenetic mechanism that can influence gene express...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2017-07-01
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| Series: | Clinical Epigenetics |
| Online Access: | http://link.springer.com/article/10.1186/s13148-017-0371-1 |