The Modulatory Effects of Pentoxifylline in Biochemical Changes Induced By 17α-Ethinyl Estradiol in the Rat Model

The Modulatory Effects of Pentoxifylline in Biochemical Changes Induced By 17α-Ethinyl Estradiol in the Rat Model

Background: Ethinylestradiol (EE) has induced cholestasis and hepatotoxicity in animal studies through reducing bile acid uptake by hepatocytes and induce of oxidative stress. Pentoxifylline (PTX) is a drug that by inhibition of release or transcription of proinflammatory cytokine cause prevents oxi...

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Bibliographic Details
Main Authors: Aysen Kor, Ebrahim Shahroozian*, Mahmood Ahmadi-Hamedani, Saeideh Naeimi
Format: Article
Language:English
Published: Arak University of Medical Sciences 2018-07-01
Series:Iranian Journal of Toxicology
Subjects:
Biochemical Parameters
Hepatotoxicity
Oxidative Stress
Pentoxifylline
17α-Ethinylestradiol
Online Access:http://ijt.arakmu.ac.ir/article-1-682-en.pdf

Internet

http://ijt.arakmu.ac.ir/article-1-682-en.pdf

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