Sinigrin Enhanced Antiasthmatic Effects of Beta Adrenergic Receptors Agonists by Regulating cAMP-Mediated Pathways

Sinigrin Enhanced Antiasthmatic Effects of Beta Adrenergic Receptors Agonists by Regulating cAMP-Mediated Pathways

Millions of patients suffer from asthma worldwide. However, the first-line drugs used to treat asthma, namely, the beta-adrenergic receptors agonists (β-agonists), are not recommended for use as monotherapy because of their severe dose-related side effects. This limitation has prompted the search fo...

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Bibliographic Details
Main Authors: Simeng Chu, Wenjuan Liu, Yujie Lu, Menglin Yan, Yingying Guo, Nianwei Chang, Min Jiang, Gang Bai
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Pharmacology
Subjects:
asthma
PDE4 inhibitor
sinigrin
airway smooth muscle
beta-adrenergic receptor agonists
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00723/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2020.00723/full

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