Regulation of cortical stability by RhoGEF3 in mitotic Sensory Organ Precursor cells in Drosophila

In epithelia, mitotic cells round up and push against their neighbors to divide. Mitotic rounding results from increased assembly of F-actin and cortical recruitment of Myosin II, leading to increased cortical stability. Whether this process is developmentally regulated is not well known. Here, we e...

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Bibliographic Details
Main Authors: Lydie Couturier, Khalil Mazouni, Fred Bernard, Charlotte Besson, Elodie Reynaud, François Schweisguth
Format: Article
Language:English
Published: The Company of Biologists 2017-12-01
Series:Biology Open
Subjects:
Online Access:http://bio.biologists.org/content/6/12/1851