Functional Effects of Receptor-Binding Domain Mutations of SARS-CoV-2 B.1.351 and P.1 Variants

Functional Effects of Receptor-Binding Domain Mutations of SARS-CoV-2 B.1.351 and P.1 Variants

The recent identification and rise to dominance of the P.1 and B.1.351 SARS-CoV-2 variants have brought international concern because they may confer fitness advantages. The same three positions in the receptor-binding domain (RBD) are affected in both variants, but where the 417 substitution differ...

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Bibliographic Details
Main Authors: Rafael Bayarri-Olmos, Ida Jarlhelt, Laust Bruun Johnsen, Cecilie Bo Hansen, Charlotte Helgstrand, Jais Rose Bjelke, Finn Matthiesen, Susanne Dam Nielsen, Kasper Karmark Iversen, Sisse Rye Ostrowski, Henning Bundgaard, Ruth Frikke-Schmidt, Peter Garred, Mikkel-Ole Skjoedt
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Immunology
Subjects:
SARS-CoV-2
RBD
ACE-2
B.1.351
P.1
variant of concern
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.757197/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.757197/full

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