Release of dengue virus genome induced by a peptide inhibitor.

Release of dengue virus genome induced by a peptide inhibitor.

Dengue virus infects approximately 100 million people annually, but there is no available therapeutic treatment. The mimetic peptide, DN59, consists of residues corresponding to the membrane interacting, amphipathic stem region of the dengue virus envelope (E) glycoprotein. This peptide is inhibitor...

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Bibliographic Details
Main Authors: Shee-Mei Lok, Joshua M Costin, Yancey M Hrobowski, Andrew R Hoffmann, Dawne K Rowe, Petra Kukkaro, Heather Holdaway, Paul Chipman, Krystal A Fontaine, Michael R Holbrook, Robert F Garry, Victor Kostyuchenko, William C Wimley, Sharon Isern, Michael G Rossmann, Scott F Michael
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3511436?pdf=render

Internet

http://europepmc.org/articles/PMC3511436?pdf=render

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