How Human Papillomavirus Replication and Immune Evasion Strategies Take Advantage of the Host DNA Damage Repair Machinery

How Human Papillomavirus Replication and Immune Evasion Strategies Take Advantage of the Host DNA Damage Repair Machinery

The DNA damage response (DDR) is a complex signalling network activated when DNA is altered by intrinsic or extrinsic agents. DDR plays important roles in genome stability and cell cycle regulation, as well as in tumour transformation. Viruses have evolved successful life cycle strategies in order t...

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Bibliographic Details
Main Authors: Valentina Bordignon, Enea Gino Di Domenico, Elisabetta Trento, Giovanna D’Agosto, Ilaria Cavallo, Martina Pontone, Fulvia Pimpinelli, Luciano Mariani, Fabrizio Ensoli
Format: Article
Language:English
Published: MDPI AG 2017-12-01
Series:Viruses
Subjects:
human papillomavirus (HPV)
DNA damage repair (DDR)
ATM
ATR
STAT-5
IFN-γ
viral immune evasion
Online Access:https://www.mdpi.com/1999-4915/9/12/390

Internet

https://www.mdpi.com/1999-4915/9/12/390

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