Frequency, suppressive capacity, recruitment and induction mechanisms of regulatory T cells in sinonasal squamous cell carcinoma and nasal inverted papilloma.

Sinonasal squamous cell carcinoma (SSCC) and nasal inverted papilloma (NIP) represent the predominant type of malignant and benign tumors in sinonasal tract, respectively. CD4+ CD25+ Foxp3+ natural regulatory T (Treg) cells might play critical role(s) in the suppression of anti-tumor immune response...

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Bibliographic Details
Main Authors: Hongfei Lou, Jugao Fang, Pingdong Li, Weiguo Zhou, Yang Wang, Erzhong Fan, Ying Li, Hong Wang, Zhongyan Liu, Lei Xiao, Chengshuo Wang, Luo Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4447263?pdf=render