The Influence of CYP2D6 Phenotype on the Pharmacokinetic Profile of Atomoxetine in Caucasian Healthy Subjects

Objective: To analyze a potential phenotypic variation within the studied group based on the pharmacokinetic profile of atomoxetine and its active metabolite, and to further investigate the impact of CYP2D6 phenotype on atomoxetine pharmacokinetics. Methods: The study was conducted as an open-label,...

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Bibliographic Details
Main Authors: Todor Ioana, Muntean Dana, Neag Maria, Bocsan Corina, Buzoianu Anca, Vlase Laurian, Leucuta Daniel, Gheldiu Ana-Maria, Popa Adina, Briciu Corina
Format: Article
Language:English
Published: Sciendo 2017-06-01
Series:Acta Medica Marisiensis
Subjects:
Online Access:https://doi.org/10.1515/amma-2017-0023