Synthesis and characterization of critical process related impurities of an asthma drug – Zafirlukast

Zafirlukast is an oral leukotriene receptor antagonist (LTRA) for the treatment of pulmonary disorders such as asthma. During the process development of zafirlukast, eight process related impurities were observed at a level of 0.1–0.15 area percent. Synthesis and characterization of these impurities...

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Bibliographic Details
Main Authors: Gilla Goverdhan, Anumula Raghupathi Reddy, Vurimidi Himabindu, Ghanta Mahesh Reddy
Format: Article
Language:English
Published: Elsevier 2014-04-01
Series:Journal of Saudi Chemical Society
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1319610311001219