Inhibition of keratinocyte differentiation by the synergistic effect of IL-17A, IL-22, IL-1α, TNFα and oncostatin M.

Inhibition of keratinocyte differentiation by the synergistic effect of IL-17A, IL-22, IL-1α, TNFα and oncostatin M.

Keratinocyte differentiation program leading to an organized epidermis plays a key role in maintaining the first line of defense of the skin. Epidermal integrity is regulated by a tight communication between keratinocytes and leucocytes, particularly under cytokine control. Imbalance of the cytokine...

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Bibliographic Details
Main Authors: Hanitriniaina Rabeony, Isabelle Petit-Paris, Julien Garnier, Christine Barrault, Nathalie Pedretti, Karline Guilloteau, Jean-François Jegou, Gérard Guillet, Vincent Huguier, Jean-Claude Lecron, François-Xavier Bernard, Franck Morel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4092099?pdf=render

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http://europepmc.org/articles/PMC4092099?pdf=render

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