Dynamic compression of chondrocyte-agarose constructs reveals new candidate mechanosensitive genes.

Articular cartilage is physiologically exposed to repeated loads. The mechanical properties of cartilage are due to its extracellular matrix, and homeostasis is maintained by the sole cell type found in cartilage, the chondrocyte. Although mechanical forces clearly control the functions of articular...

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Bibliographic Details
Main Authors: Carole Bougault, Elisabeth Aubert-Foucher, Anne Paumier, Emeline Perrier-Groult, Ludovic Huot, David Hot, Martine Duterque-Coquillaud, Frédéric Mallein-Gerin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3355169?pdf=render