Behavioral and Molecular Analysis of Antioxidative Potential of Rosmarinic Acid Against Methamphetamine-induced Augmentation of Casp3a mRNA in the Zebrafish Brain

Behavioral and Molecular Analysis of Antioxidative Potential of Rosmarinic Acid Against Methamphetamine-induced Augmentation of Casp3a mRNA in the Zebrafish Brain

Introduction: Methamphetamine (MA) acts as a powerful oxidant agent, while Rosmarinic Acid (RA) is an effective herbal antioxidant. Oxidative stress-mediated by MA results in apoptosis, and caspase-3 is one of the critical enzymes in the apoptosis process. MA can epigenetically alter gene regulation...

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Bibliographic Details
Main Authors: Vida Nikshenas Shahrestani, Mohammad Haddadi, Ali Reza Samzadeh Kermani
Format: Article
Language:English
Published: Iran University of Medical Sciences 2021-03-01
Series:Basic and Clinical Neuroscience
Subjects:
methamphetamine
casp3a
rosmarinic acid
zinc oxide
chitosan nanoparticle
zebrafish
behavioral test
Online Access:http://bcn.iums.ac.ir/article-1-1473-en.html

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http://bcn.iums.ac.ir/article-1-1473-en.html

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