Binding-induced folding of a natively unstructured transcription factor.

Transcription factors are central components of the intracellular regulatory networks that control gene expression. An increasingly recognized phenomenon among human transcription factors is the formation of structure upon target binding. Here, we study the folding and binding of the pKID domain of...

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Bibliographic Details
Main Authors: Adrian Gustavo Turjanski, J Silvio Gutkind, Robert B Best, Gerhard Hummer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-04-01
Series:PLoS Computational Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18404207/?tool=EBI