Progress and challenges in the computational prediction of gene function using networks: 2012-2013 update [v1; ref status: indexed, http://f1000r.es/1w9]

In an opinion published in 2012, we reviewed and discussed our studies of how gene network-based guilt-by-association (GBA) is impacted by confounds related to gene multifunctionality. We found such confounds account for a significant part of the GBA signal, and as a result meaningfully evaluating a...

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Bibliographic Details
Main Authors: Paul Pavlidis, Jesse Gillis
Format: Article
Language:English
Published: F1000 Research Ltd 2013-10-01
Series:F1000Research
Subjects:
Online Access:http://f1000research.com/articles/2-230/v1