A missense mutation of ErbB2 produces a novel mouse model of stillbirth associated with a cardiac abnormality but lacking abnormalities of placental structure.

BACKGROUND:In humans, stillbirth describes the death of a fetus before birth after 28 weeks gestation, and accounts for approximately 2.6 million deaths worldwide annually. In high-income countries, up to half of stillbirths have an unknown cause and are described as "unexplained stillbirths&qu...

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Bibliographic Details
Main Authors: Heba Shawer, Esther Aiyelaagbe, Christopher Clowes, Samantha C Lean, Yinhui Lu, Karl E Kadler, Alan Kerby, Mark R Dilworth, Kathryn E Hentges, Alexander E P Heazell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0233007