Carbamazepine protects against neuronal hyperplasia and abnormal gene expression in the megencephaly mouse

Carbamazepine (CBZ) is an anticonvulsant drug used to treat epilepsy and mood disorders. However, it can cause birth defects like reduced head circumference. It was recently shown to protect against brain overgrowth and seizure-induced abnormal plasticity in the megalencephalic mice Kv1.1mceph/mceph...

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Bibliographic Details
Main Authors: Malin Almgren, Jens R. Nyengaard, Bengt Persson, Catharina Lavebratt
Format: Article
Language:English
Published: Elsevier 2008-12-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996108001836