Histone H3K4 Methyltransferases as Targets for Drug-Resistant Cancers

The KMT2 (MLL) family of proteins, including the major histone H3K4 methyltransferase found in mammals, exists as large complexes with common subunit proteins and exhibits enzymatic activity. SMYD, another H3K4 methyltransferase, and SET7/9 proteins catalyze the methylation of several non-histone ta...

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Bibliographic Details
Main Authors: Liu Yang, Mingli Jin, Kwang Won Jeong
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Biology
Subjects:
Online Access:https://www.mdpi.com/2079-7737/10/7/581