Inflammatory Pathophysiology as a Contributor to Myeloproliferative Neoplasms

Inflammatory Pathophysiology as a Contributor to Myeloproliferative Neoplasms

Myeloid neoplasms, including acute myeloid leukemia (AML), myeloproliferative neoplasms (MPNs), and myelodysplastic syndromes (MDS), feature clonal dominance and remodeling of the bone marrow niche in a manner that promotes malignant over non-malignant hematopoiesis. This take-over of hematopoiesis...

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Bibliographic Details
Main Authors: Daniel Arthur Corpuz Fisher, Jared Scott Fowles, Amy Zhou, Stephen Tracy Oh
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Immunology
Subjects:
myeloproliferative neoplasms
myelofibrosis
cytokines
intracellular signaling
JAK2
NF kappa B (NFκB)
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.683401/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.683401/full

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