Diversity-oriented synthesis of spirothiazolidinediones and their biological evaluation

Diversity-oriented synthesis of spirothiazolidinediones and their biological evaluation

We report a new synthetic approach to assemble spirothiazolidinediones via a [2 + 2 + 2] cyclotrimerization reaction and the derivatives were further functionalized through DA chemistry and click reaction. Using flow cytometry, it was shown for the first time that the new benzyl alcohol derivatives...

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Bibliographic Details
Main Authors: Sambasivarao Kotha, Gaddamedi Sreevani, Lilya U. Dzhemileva, Milyausha M. Yunusbaeva, Usein M. Dzhemilev, Vladimir A. D’yakonov
Format: Article
Language:English
Published: Beilstein-Institut 2019-11-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
apoptosis
biologically active
[2 + 2 + 2] cycloaddition
flow cytometry
spiro thiazolidinedione
Online Access:https://doi.org/10.3762/bjoc.15.269

Internet

https://doi.org/10.3762/bjoc.15.269

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