Emerging immune and cell death mechanisms in stroke: Saponins as therapeutic candidates

The complexity of the ischemic cascade is based on the integrated crosstalk of every cell type in the neurovascular unit. Depending on the features of the ischemic insult, several cell death mechanisms are triggered, such as apoptosis, necroptosis, ferroptosis/oxytosis, ETosis or pyroptosis, leading...

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Bibliographic Details
Main Authors: Laura García-Pupo, Emily Van San, René Delgado-Hernández, Tom Vanden Berghe, Wim Vanden Berghe
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Brain, Behavior, & Immunity - Health
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666354620301174