RNase HI Is Essential for Survival of Mycobacterium smegmatis.

RNases H are involved in the removal of RNA from RNA/DNA hybrids. Type I RNases H are thought to recognize and cleave the RNA/DNA duplex when at least four ribonucleotides are present. Here we investigated the importance of RNase H type I encoding genes for model organism Mycobacterium smegmatis. By...

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Bibliographic Details
Main Authors: Alina E Minias, Anna M Brzostek, Malgorzata Korycka-Machala, Bozena Dziadek, Piotr Minias, Malini Rajagopalan, Murty Madiraju, Jaroslaw Dziadek
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4429107?pdf=render