microRNA expression patterns reveal differential expression of target genes with age.

Recent evidence supports a role for microRNAs (miRNAs) in regulating the life span of model organisms. However, little is known about how these small RNAs contribute to human aging. Here, we profiled the expression of over 800 miRNAs in peripheral blood mononuclear cells from young and old individua...

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Bibliographic Details
Main Authors: Nicole Noren Hooten, Kotb Abdelmohsen, Myriam Gorospe, Ngozi Ejiogu, Alan B Zonderman, Michele K Evans
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-05-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2873959?pdf=render