Suppressor of fused controls perinatal expansion and quiescence of future dentate adult neural stem cells

Suppressor of fused controls perinatal expansion and quiescence of future dentate adult neural stem cells

Adult hippocampal neurogenesis requires the quiescent neural stem cell (NSC) pool to persist lifelong. However, establishment and maintenance of quiescent NSC pools during development is not understood. Here, we show that Suppressor of Fused (Sufu) controls establishment of the quiescent NSC pool du...

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Bibliographic Details
Main Authors: Hirofumi Noguchi, Jesse Garcia Castillo, Kinichi Nakashima, Samuel J Pleasure
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-04-01
Series:eLife
Subjects:
stem cell
dentate gyrus
sonic hedgehog
hippocampal development
Online Access:https://elifesciences.org/articles/42918

Internet

https://elifesciences.org/articles/42918

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