Successful Suppression of the Early Rejection of Pig Islets in Monkeys

Primary nonfunction (PNF) is seen very frequently after xenogeneic transplantation of islets of Langerhans. In a pig-to-rat model we recently observed that no PNF occurs when the islets are kept in culture at 37°C for 1–2 weeks prior to transplantation. In order to investigate the rejection mechanis...

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Bibliographic Details
Main Authors: Josephine K. R. A. Rijkelijkhuizen, Eelco Bouwman, Michel P. M. Van Der Burg, Jan Ringers, Miriam A. Ossevoort, Eva M. Kuhn, Pat Frost, Margreet Jonker
Format: Article
Language:English
Published: SAGE Publishing 2000-11-01
Series:Cell Transplantation
Online Access:https://doi.org/10.1177/096368970000900618