Transcriptional changes and preservation of bone mass in hibernating black bears

Abstract Physical inactivity leads to losses of bone mass and strength in most mammalian species. In contrast, hibernating bears show no bone loss over the prolonged periods (4–6 months) of immobility during winter, which suggests that they have adaptive mechanisms to preserve bone mass. To identify...

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Bibliographic Details
Main Authors: Anna V. Goropashnaya, Øivind Tøien, Thiruvarangan Ramaraj, Anitha Sundararajan, Faye D. Schilkey, Brian M. Barnes, Seth W. Donahue, Vadim B. Fedorov
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-87785-9