Inhibition of the progesterone nuclear receptor during the bone linear growth phase increases peak bone mass in female mice.

Augmentation of the peak bone mass (PBM) may be one of the most effective interventions to reduce the risk of developing osteoporosis later in life; however treatments to augment PBM are currently limited. Our study evaluated whether a greater PBM could be achieved either in the progesterone nuclear...

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Bibliographic Details
Main Authors: Wei Yao, Weiwei Dai, Mohammad Shahnazari, Aaron Pham, Zhiqiang Chen, Haiyan Chen, Min Guan, Nancy E Lane
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-07-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2895664?pdf=render