Increased hypothalamic microglial activation after viral-induced pneumococcal lung infection is associated with excess serum amyloid A production

Increased hypothalamic microglial activation after viral-induced pneumococcal lung infection is associated with excess serum amyloid A production

Abstract Background It is well established that lung pathology and inflammation are more severe during respiratory infections complicated by the presence of both bacteria and viruses. Whilst co-infection can result in invasive pneumococcal disease and systemic inflammation, the neuroinflammatory con...

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Bibliographic Details
Main Authors: Hao Wang, Melissa Blackall, Luba Sominsky, Sarah J. Spencer, Ross Vlahos, Melissa Churchill, Steven Bozinovski
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Journal of Neuroinflammation
Subjects:
Microglia
Neuroinflammation
Pneumonia
Serum amyloid A
Resolvin-D1
Online Access:http://link.springer.com/article/10.1186/s12974-018-1234-1

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http://link.springer.com/article/10.1186/s12974-018-1234-1

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