Large Animal Models for Foamy Virus Vector Gene Therapy

Foamy virus (FV) vectors have shown great promise for hematopoietic stem cell (HSC) gene therapy. Their ability to efficiently deliver transgenes to multi-lineage long-term repopulating cells in large animal models suggests they will be effective for several human hematopoietic diseases. Here, we re...

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Bibliographic Details
Main Authors: Peter A. Horn, Brian C. Beard, Hans-Peter Kiem, Grant D. Trobridge
Format: Article
Language:English
Published: MDPI AG 2012-12-01
Series:Viruses
Subjects:
Online Access:http://www.mdpi.com/1999-4915/4/12/3572