Quantitative in situ measurement of estrogen receptor mRNA predicts response to tamoxifen.

<h4>Purpose</h4>Quantification of mRNA has historically been done by reverse transcription polymerase chain reaction (RT-PCR). Recently, a robust method of detection of mRNA utilizing in situ hybridization has been described that is linear and shows high specificity with low background....

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Bibliographic Details
Main Authors: Jennifer M Bordeaux, Huan Cheng, Allison W Welsh, Bruce G Haffty, Donald R Lannin, Xingyong Wu, Nan Su, Xiao-Jun Ma, Yuling Luo, David L Rimm
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22606272/?tool=EBI