Chronic lung inflammation primes humoral immunity and augments antipneumococcal resistance

Abstract Airway epithelial cells (AECs) display remarkable plasticity in response to infectious stimuli and their functional adaptations are critical for antimicrobial immunity. However, the roles of AECs and humoral mediators to host defense in non-communicable lung inflammation remain elusive. We...

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Bibliographic Details
Main Authors: Julia D. Boehme, Sabine Stegemann-Koniszewski, Andrea Autengruber, Nicole Peters, Josef Wissing, Lothar Jänsch, Andreas Jeron, Dunja Bruder
Format: Article
Language:English
Published: Nature Publishing Group 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-05212-4