A new pooling strategy for high-throughput screening: the Shifted Transversal Design

<p>Abstract</p> <p>Background</p> <p>In binary high-throughput screening projects where the goal is the identification of low-frequency events, beyond the obvious issue of efficiency, false positives and false negatives are a major concern. Pooling constitutes a natural...

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Bibliographic Details
Main Author: Thierry-Mieg Nicolas
Format: Article
Language:English
Published: BMC 2006-01-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/7/28