TNF-α Inhibitors Decrease Classical CD14hiCD16− Monocyte Subsets in Highly Active, Conventional Treatment Refractory Rheumatoid Arthritis and Ankylosing Spondylitis

TNF-α Inhibitors Decrease Classical CD14hiCD16− Monocyte Subsets in Highly Active, Conventional Treatment Refractory Rheumatoid Arthritis and Ankylosing Spondylitis

Monocytes are pivotal cells in inflammatory joint diseases. We aimed to determine the effect of TNF-α inhibitors (TNFi) on peripheral blood monocyte subpopulations and their activation in ankylosing spondylitis (AS) and rheumatoid arthritis (RA) patients with high disease activity. To addr...

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Bibliographic Details
Main Authors: Bogdan Batko, Agata Schramm-Luc, Dominik S. Skiba, Tomasz P. Mikolajczyk, Mateusz Siedlinski
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:International Journal of Molecular Sciences
Subjects:
rheumatoid arthritis
ankylosing spondylitis
tumor necrosis factor inhibitor
disease activity
monocytes
Online Access:http://www.mdpi.com/1422-0067/20/2/291

Internet

http://www.mdpi.com/1422-0067/20/2/291

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