Cardiac Fibroblast p38 MAPK: A Critical Regulator of Myocardial Remodeling

Cardiac Fibroblast p38 MAPK: A Critical Regulator of Myocardial Remodeling

The cardiac fibroblast is a remarkably versatile cell type that coordinates inflammatory, fibrotic and hypertrophic responses in the heart through a complex array of intracellular and intercellular signaling mechanisms. One important signaling node that has been identified involves p38 MAPK; a famil...

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Bibliographic Details
Main Authors: Neil A. Turner, Nicola M. Blythe
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Journal of Cardiovascular Development and Disease
Subjects:
cardiac remodeling
extracellular matrix
fibroblast
fibrosis
heart
hypertrophy
inflammation
myofibroblast
p38 MAP kinase
signal transduction
stress-activated protein kinase
transcription factor
Online Access:https://www.mdpi.com/2308-3425/6/3/27

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https://www.mdpi.com/2308-3425/6/3/27

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