INVOLVEMENT OF PERFORIN/GRANZYME B-DEPENDENT SIGNALING PATHWAY IN CYTOTOXIC ACTIVITY OF DENDRITIC CELLS TOWARDS HUMAN GLIOBLASTOMA CELLS
Granule-mediated cytotoxicity of effector cells is a universal mechanism of tumor growth inhibition and induction of tumor cell death. The aim of present study was to evaluate expression of lytic molecules in DCs generated in presence of IFNα (IFN-DCs), and to analyze the role of granule-mediate...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
SPb RAACI
2017-08-01
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| Series: | Medicinskaâ Immunologiâ |
| Subjects: | |
| Online Access: | https://www.mimmun.ru/mimmun/article/view/1313 |