On-Line Optimal Input Design Increases the Efficiency and Accuracy of the Modelling of an Inducible Synthetic Promoter

Synthetic biology seeks to design biological parts and circuits that implement new functions in cells. Major accomplishments have been reported in this field, yet predicting a priori the in vivo behaviour of synthetic gene circuits is major a challenge. Mathematical models offer a means to address t...

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Bibliographic Details
Main Authors: Lucia Bandiera, Zhaozheng Hou, Varun B. Kothamachu, Eva Balsa-Canto, Peter S. Swain, Filippo Menolascina
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:Processes
Subjects:
Online Access:http://www.mdpi.com/2227-9717/6/9/148