Topological Regulation of Synaptic AMPA Receptor Expression by the RNA-Binding Protein CPEB3

Topological Regulation of Synaptic AMPA Receptor Expression by the RNA-Binding Protein CPEB3

Synaptic receptors gate the neuronal response to incoming signals, but they are not homogeneously distributed on dendrites. A spatially defined receptor distribution can preferentially amplify certain synaptic inputs, resize receptive fields of neurons, and optimize information processing within a n...

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Bibliographic Details
Main Authors: Iaroslav Savtchouk, Lu Sun, Crhistian L. Bender, Qian Yang, Gábor Szabó, Sonia Gasparini, Siqiong June Liu
Format: Article
Language:English
Published: Elsevier 2016-09-01
Series:Cell Reports
Subjects:
AMPA receptor
subunit composition
CPEB3
dendritic gradient
topostatic plasticity
GluA2
cerebellar stellate cell
PKC
calcium imaging
action potentials
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124716312037

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http://www.sciencedirect.com/science/article/pii/S2211124716312037

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