Understanding the mechanism of glucose-induced relief of Rgt1-mediated repression in yeast
The yeast Rgt1 repressor inhibits transcription of the glucose transporter (HXT) genes in the absence of glucose. It does so by recruiting the general corepressor complex Ssn6-Tup1 and the HXT corepressor Mth1. In the presence of glucose, Rgt1 is phosphorylated by the cAMP-activated protein kinase A...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2014-01-01
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Series: | FEBS Open Bio |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211546313000788 |