Understanding the mechanism of glucose-induced relief of Rgt1-mediated repression in yeast

The yeast Rgt1 repressor inhibits transcription of the glucose transporter (HXT) genes in the absence of glucose. It does so by recruiting the general corepressor complex Ssn6-Tup1 and the HXT corepressor Mth1. In the presence of glucose, Rgt1 is phosphorylated by the cAMP-activated protein kinase A...

Full description

Bibliographic Details
Main Authors: Adhiraj Roy, David Jouandot II, Kyu Hong Cho, Jeong-Ho Kim
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:FEBS Open Bio
Subjects:
HXT
Online Access:http://www.sciencedirect.com/science/article/pii/S2211546313000788