Geldanamycin derivative ameliorates high fat diet-induced renal failure in diabetes.

Diabetic nephropathy is a serious complication of longstanding diabetes and its pathogenesis remains unclear. Oxidative stress may play a critical role in the pathogenesis and progression of diabetic nephropathy. Our previous studies have demonstrated that polyunsaturated fatty acids (PUFA) induce p...

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Bibliographic Details
Main Authors: Hong-Mei Zhang, Howard Dang, Amrita Kamat, Chih-Ko Yeh, Bin-Xian Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3295767?pdf=render