NF90 binds the dengue virus RNA 3' terminus and is a positive regulator of dengue virus replication.

Viral RNA translation and replication are regulated by sequence and structural elements in the 5' and 3' untranslated regions (UTR) and by host cell and/or viral proteins that bind them. Dengue virus has a single-stranded RNA genome with positive polarity, a 5' m7GpppG cap, and a cons...

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Bibliographic Details
Main Authors: Raúl C Gomila, Glover W Martin, Lee Gehrke
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-02-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3046124?pdf=render