Molecular Pathology and Pharmacological Treatment of Autism Spectrum Disorder-Like Phenotypes Using Rodent Models

Molecular Pathology and Pharmacological Treatment of Autism Spectrum Disorder-Like Phenotypes Using Rodent Models

Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental disorder with a high prevalence rate. The core symptoms of ASD patients are impaired social communication and repetitive behavior. Genetic and environmental factors contribute to pathophysiology of ASD. Regarding environmental risk...

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Bibliographic Details
Main Authors: Hsiao-Ying Kuo, Fu-Chin Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Cellular Neuroscience
Subjects:
autism
valproic acid
excitatory/inhibitory imbalance
endocannabinoid system
mTOR signaling
Wnt signaling
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2018.00422/full

Internet

https://www.frontiersin.org/article/10.3389/fncel.2018.00422/full

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