Identification of drug-target interaction by a random walk with restart method on an interactome network

Abstract Background Identification of drug-target interactions acts as a key role in drug discovery. However, identifying drug-target interactions via in-vitro, in-vivo experiments are very laborious, time-consuming. Thus, predicting drug-target interactions by using computational approaches is a go...

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Bibliographic Details
Main Authors: Ingoo Lee, Hojung Nam
Format: Article
Language:English
Published: BMC 2018-06-01
Series:BMC Bioinformatics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12859-018-2199-x