Temsirolimus in the treatment of advanced renal cell carcinoma
Temsirolimus is a novel inhibitor of mammalian target of rapamycin (mTOR), which is a central regulator of the response of tumour cells to growth and survival signals. When heavily pretreated patients with advanced solid tumours received intravenous (IV) temsirolimus over a broad dose range, antitum...
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Format: | Article |
Language: | English |
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PAGEPress Publications
2011-12-01
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Series: | Oncology Reviews |
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Online Access: | http://oncologyreviews.org/index.php/or/article/view/142 |