Temsirolimus in the treatment of advanced renal cell carcinoma

Temsirolimus is a novel inhibitor of mammalian target of rapamycin (mTOR), which is a central regulator of the response of tumour cells to growth and survival signals. When heavily pretreated patients with advanced solid tumours received intravenous (IV) temsirolimus over a broad dose range, antitum...

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Bibliographic Details
Main Author: Bernard J. Escudier
Format: Article
Language:English
Published: PAGEPress Publications 2011-12-01
Series:Oncology Reviews
Subjects:
Online Access:http://oncologyreviews.org/index.php/or/article/view/142