Role of nicotine dependence in the association between the dopamine receptor gene DRD3 and major depressive disorder.

The aims of this study were to analyze associations of dopamine receptor genes (DRD1-5) with Major Depressive Disorder (MDD) and nicotine dependence (ND), and to investigate whether ND moderates genetic influences on MDD.The sample was ascertained from the Finnish Twin Cohort. Twin pairs concordant...

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Bibliographic Details
Main Authors: Tellervo Korhonen, Anu Loukola, Juho Wedenoja, Emma Nyman, Antti Latvala, Ulla Broms, Anja Häppölä, Tiina Paunio, Andrew J Schrage, Jaqueline M Vink, Hamdi Mbarek, Dorret I Boomsma, Brenda W J H Penninx, Michele L Pergadia, Pamela A F Madden, Jaakko Kaprio
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4057087?pdf=render