Translational regulation of specific mRNAs controls feedback inhibition and survival during macrophage activation.

For a rapid induction and efficient resolution of the inflammatory response, gene expression in cells of the immune system is tightly regulated at the transcriptional and post-transcriptional level. The control of mRNA translation has emerged as an important determinant of protein levels, yet its ro...

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Bibliographic Details
Main Authors: Johanna Schott, Sonja Reitter, Janine Philipp, Katharina Haneke, Heiner Schäfer, Georg Stoecklin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-06-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4063670?pdf=render