βν integrin inhibits chronic and high level activation of JNK to repress senescence phenotypes in Drosophila adult midgut.

Proper control of adult stem cells including their proliferation and differentiation is crucial in maintaining homeostasis of well-organized tissues/organs throughout an organism's life. The Drosophila adult midgut has intestinal stem cells (ISCs), which have been exploited as a simple model sy...

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Bibliographic Details
Main Authors: Takashi Okumura, Koji Takeda, Kiichiro Taniguchi, Takashi Adachi-Yamada
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3930726?pdf=render