Bioavailability and Pharmacokinetics of Once-Daily Amantadine Extended-Release Tablets in Healthy Volunteers: Results from Three Randomized, Crossover, Open-Label, Phase 1 Studies

Bioavailability and Pharmacokinetics of Once-Daily Amantadine Extended-Release Tablets in Healthy Volunteers: Results from Three Randomized, Crossover, Open-Label, Phase 1 Studies

Abstract Introduction In February 2018, OS320—an amantadine extended-release (ER) tablet formulation with once-daily morning administration—was approved for the treatment of Parkinson’s disease and drug-induced extrapyramidal reactions in adults. The purpose of this study was to describe three phase...

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Bibliographic Details
Main Authors: Tina deVries, Angela Dentiste, Lata Handiwala, David Jacobs
Format: Article
Language:English
Published: Adis, Springer Healthcare 2019-08-01
Series:Neurology and Therapy
Subjects:
Absorption
Amantadine
Bioavailability
Bioequivalence
Pharmacokinetics
Online Access:http://link.springer.com/article/10.1007/s40120-019-0144-1

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http://link.springer.com/article/10.1007/s40120-019-0144-1

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